… Moreover, the sensitization of cisplatin‑induced cytotoxicity in U2OS cells … p14ARF sensitizes
human osteosarcoma cells to cisplatin‑induced apoptosis in a p53‑independent manner. …

… To explore the effects of tumor suppressor p14ARF on chemosensitivity of human osteosarcoma
U2OS cells to … U2OS cells expressing no p14ARF and U2OS-ARF cells expressing …

… of tumor suppressor p14ARF on cisplatin-induced apoptosis in human osteosarcoma cells
with its … mechanisms to provide evidences for increasing chemosensitivity of osteosarcoma. …

… role in enhancing cells to cisplatin-induced cell death. … of p21 expression in an entirely
p53-independent fashion, as the … of p14 ARF in sensitizing p53 mutated osteosarcoma cells to …

… that p14ARF expression sensitized cells to the pro-apoptotic … in a p53-independent manner,
we investigated the impact of … additional cellular stresses, such as cisplatin-induced DNA …

… to cisplatin in a p53-independent manner, suggesting that DMTF1α could sensitize cells
towards cisplatin in an p14 ARF -dependent/p53-independent fashion [19]. Moreover, early …

… siRNA would be predicted to significantly sensitize glioblastoma cells with TP53 mutations
to cisplatin treatment, resulting in much more rapid entry into apoptosis, which we observed (…

… can induce autophagy in a p53-independent manner [153]. … p14ARF protein levels in
ovarian and lung cancer cell lines … -1 sensitizes cisplatininduced lung cancer cell apoptosis via …

… following MDM2 overexpression, p14ARF deletion/hy… could be critical in cisplatin-induced
apoptosis. In particular, it … Although in principle p73 could act in a p53-independent manner…

… will allow cancer cells to evade cisplatin-induced cell death [14… of cell death via p53 signaling,
a p53-independent apoptotic … -methylating agent decitabine sensitized human colon tumor …